陈鹏 副教授,硕士生导师
资源昆虫高效养殖与利用全国重点实验室
Contact Us(联系方式):
E-mail(邮件): pjchen@swu.edu.cn
教育背景
2010-2014 西南大学,遗传学专业,博士
2008-2010 西南大学,特种经济动物饲养专业,硕士
2004-2008 西南大学,蚕学专业,学士
工作经历
2019-至今 资源昆虫高效养殖与利用全国重点实验室,副教授
2016-2019 西南大学,助理研究员
2014-2016 西南大学,师资博士后
研究领域
围绕家蚕细胞生物学和抗性遗传,以家蚕细胞周期、细胞凋亡,以及抗病性和抗逆性为切入点,致力于家蚕丝腺高效核内复制机制、细胞凋亡在BmNPV入侵中的作用机制和抗高温基因挖掘等研究。
学术贡献
主要从事家蚕细胞凋亡与周期调控、抗逆性及抗病性机制研究。鉴定了多个参与家蚕丝腺核内复制的关键信号通路和调控因子;证实了细胞凋亡在BmNPV与宿主互作过程中行使重要功能,并解析了相关凋亡抑制基因、长链非编码RNA及microRNA等调控BmNPV增殖复制的分子机制;揭示了DNA甲基化在家蚕对环境胁迫的反应中起重要作用,并鉴定了多个家蚕耐高温基因;创制高产丝量、抗BmNPV、耐高温等家蚕新素材20余个。主持国家重点研发子课题、国家自然科学基金青年科学基金项目、中国博士后科学基金面上项目、重庆市自然科学基金项目、重庆市茧丝绸发展项目、重庆市博士后科研特别资助项目、中央高校基本科研业务费专项资金项目,以及相关横向课题10余项。作为研究骨干参研国家“863”计划项目、国家自然科学基金重点项目、国家自然科学基金联合基金重点项目等多项科研项目;在Int J Biol Macromol、Pest Manag Sci、Insect Sci、Pestic Biochem Physiol、Heredity、Sci Rep、Insect Mol Biol、Antiviral Res等国内外知名期刊发表SCI论文40余篇。
荣誉奖励
2022 重庆市自然科学奖二等奖(排名第三)
2021 第一届全国博士后创新创业大赛银奖(排名第二)
2021 全国创新创业优秀博士后
代表性论文
1) Qiao Wu#, Xia Jiang#, Lan-Xing Wang, Zhen-Ye Liu, Wen-Yu Yang, Cai Jing, Yu Xiao, Yan Zhu, Zhan-Qi Dong, Cheng Lu, Min-Hui Pan*, Peng Chen*. Bombyx mori Suppressor of Hairless is involved in the regulation of the silkworm cell cycle and endoreplication of the silk glands. Int J Biol Macromol, 2024, 268(Pt 2):131819.
2) Wen-Yu Yang, Zhen-Ye Liu, Yan Zhu, Yu Xiao, Wen-Fu Xiao, Liang Tang, Zhan-Qi Dong, Min-Hui Pan, Cheng Lu*, Peng Chen*. MicroRNA bmo-miR-31-5p inhibits apoptosis and promotes BmNPV proliferation by targeting the CYP9e2 gene of Bombyx mori. Pest Manag Sci, 2024, 80(9):4564-4574.
3) Zhenye Liu#, Cong Li#, Wenyu Yang, Qiao Wu, Wenfu Xiao, Yan Zhu, Qiongqiong Wei, Zhanqi Dong, Guizheng Zhang, Cheng Lu, Min-Hui Pan*, Peng Chen*. The Bombyx mori singed gene is involved in the high-temperature resistance of silkworms. Insects, 2024, 15(4):264.
4) Peng Chen#, Min Cai#, Yu-Jie Feng, Cong Li, Zhan-Qi Dong, Wen-Fu Xiao, Liang Tang, Yan Zhu, Ting Tian, Bo-Yuan Deng, Min-Hui Pan*, Cheng Lu*. Apoptosis-related long non-coding RNA LINC5438 of Bombyx mori promotes the proliferation of BmNPV. Pestic Biochem Physiol, 2023, 191:105380.
5) Peng Chen, Ling Wang, Yan-Bi Long, Guang-Yan Liang, Xiu Yang, Zhan-Qi Dong, Xia Jiang, Yan Zhu, Min-Hui Pan*, Cheng Lu*. E2F4 regulates the cell cycle and DNA replication in the silkworm, Bombyx mori. Insect Sci, 2022, 29(4):1006-1016.
6) Chen P#, Xiao WF#, Pan MH, Xiao JS, Feng YJ, Dong ZQ, Zou BX, Zhou L, Zhang YH*, Lu C*. Comparative genome-wide DNA methylation analysis reveals epigenomic differences in response to heat-humidity stress in Bombyx mori. Int J Biol Macromol, 2020, 164:3771-3779.
7) Chen P#, Kang TT#, Bao XY, Dong ZQ, Zhu Y, Xiao WF, Min-Hui Pan*, Cheng Lu*. Evolutionary and functional analyses of the interaction between the Bombyx mori inhibitor of apoptosis (IAP) and nucleopolyhedrovirus IAPs. Insect Sci, 2020, 27(3):463-474.
8) Chen P#, Tong XL#, Fu MY, Hu H, Song JB, He SZ, Gai TT, Dai FY*, Lu C*. Molecular mapping and characterization of the silkworm apodal mutant. Scientific Reports, 2016, 6: 18956.
9) Chen P#, Tong XL#, Li DD, Fu MY, He SZ, Hu H, Xiang ZH, Lu C*, Dai FY*. Antennapedia is involved in the development of thoracic legs and segmentation in the silkworm, Bombyx mori. Heredity, 2013, 111(3): 182-188.
10) Chen P, Tong XL, Li DD, Liang PF, Fu MY, Li CF, Hu H, Xiang ZH, Lu C*, Dai FY*. Fine mapping of a supernumerary proleg mutant (ECs-l) and comparative expression analysis of the abdominal-A gene in silkworm, Bombyx mori. Insect Molecular Biology, 2013, 22(5): 497-504.