宋江波 副教授，硕士生导师

资源昆虫高效养殖与利用全国重点实验室

Contact Us（联系方式）：023-68250551
E-mail（邮件）: jiangbosong@swu.edu.cn

教育背景

2011-2017 西南大学，资源昆虫高效养殖与利用全国重点实验室 生理学专业，博士学位

2007-2011 周口师范学院生命科学系，生物科学专业 学士

工作经历

2022-今 资源昆虫高效养殖与利用全国重点实验室 副教授、硕士生导师

2021-今 资源昆虫高效养殖与利用全国重点实验室 副教授

2017-2020 资源昆虫高效养殖与利用全国重点实验室 畜牧学 博士后

研究领域

1. 利用家蚕等物种探究衰老和寿命调节的保守性分子机制

2. 蚕体强健性控制基因的挖掘和分子改良

3. 以家蚕为实验动物发掘疾病基因，构建疾病模型，评价药物药效和药理

学术贡献

一直致力于家蚕分子生理与改良研究，并以提升蚕体强健性相关基因发掘和作用机制研究为主要内容。开创了家蚕作为保健类中药及其活性物质评价的研究，阐释了8种活性物质对蚕体强健性调节的作用及生理机制。鉴定了10个能够增强蚕体强健性的重要基因，揭示了7条增强蚕体强健性的新路径，初步构建了蚕体强健性的调控网络，突破了单一基因或信号路径的研究局限，为家蚕强健性的分子改良提供了重要理论基础。发现了影响强健性的新基因OSER1，并在家蚕、线虫、果蝇等多物种中研究揭示了其通过增强机体氧化应激防御而提升强健性及延长健康寿命的保守性机制，展示了OSER1作为促进健康生存的关键调控靶标的重要潜力，为蚕体强健性的分子改良带来重要前景。以第一作者在Nature Communications、BMC Medicine、Journal of Pharmaceutical Analysis、Aging and Disease等领域著名期刊发表论文14篇。主持包括国家自然科学基金面上项目、青年基金项目和西南大学基础学科青年人才项目（简称U40）、西南大学第一批高层次后备人才计划等在内的科研项目8项，授权发明专利1项，做国际学术报告7次，国内学术报告7次，长期担任BMC Genomics、Frontiers in aging Neuroscience等期刊审稿人。

荣誉奖励

2023年，获重庆市“巴渝学者”青年学者

2024.12，研究成果入选“重庆市2024年度基础研究代表性成果”

2024.09，获西南大学2022-2024年度优秀教师

2023.08，第7届Asia-Pacific Congress of Sericulture and Insect Biotechnology优秀报告奖

2019.03，第6届Asia-Pacific Congress of Sericulture and Insect Biotechnology优秀报告奖

2024.01-至今，重庆市昆虫学会理事

2024.01-至今，农业生物技术学报青年编委

2024.01-至今，中国遗传学会会员

代表性论文

1) Jiangbo Song*, Zhiquan Li*, Lei Zhou, Xin Chen, Wei Qi Guinevere Sew, Héctor Herranz, Zilu Ye, Jesper Velgaard Olsen, Yuan Li, Marianne Nygaard, Kaare Christensen, Xiaoling Tong, Vilhelm A. Bohr, Lene Juel Rasmussen^§, Fangyin Dai^§. FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species. Nature Communications. 2024, 15: 7144.

2) Song Jiangbo*, Liu Lian*, Li Zhiquan*, Mao Ting, Zhang Jianfei, Zhou Lei, Chen Xin, Shang Yunzhu, Sun Tao, Luo Yuxin, Jiang Yu, Tan Duan, Tong Xiaoling and Dai Fangyin^§. Lycium barbarum polysaccharide improves dopamine metabolism and symptoms in an MPTP-induced model of Parkinson’s disease. BMC Medicine. 2022, 20: 412. Doi:10.1186/s12916-022-02621-9

3) Song Jiangbo*, Chen Min*, Li Zhiquan, Zhang Jianfei, Hu Hai, Tong Xiaoling^§, Dai Fangyin^§. Astragalus Polysaccharide extends lifespan via mitigating endoplasmic reticulum stress in the Silkworm, Bombyx mori. Aging and Disease. 2019, 10(2): 1187-1198.

4) Song Jiangbo*, Liu Lian*, Hao Kaige, Mao Shuang, Tang Yongxi, Tong Xiaoling, Dai Fangyin^§. Resveratrol elongates the lifespan and improves antioxidant activity in the silkworm, Bombyx mori. Journal of Pharmaceutical Analysis. 2021, 11: 374-382.

5) Song Jiangbo*, Jiang Guihua*, Zhang Jianfei, Guo Jieshu, Li Zheng, Hao Kaige, Liu Lian, Cheng Zilin, Tong Xiaoling, Dai Fangyin^§. Metformin prolongs lifespan through remodeling the energy distribution strategy in silkworm, Bombyx mori. Aging-US, 2019, 11(1): 240-248.

6) Song Jiangbo*, Hao Kaige*, Chen Xin, Zhang Yanhua, Cheng Zilin, Mao Shuang, Tang Yongxi, Tong Xiaoling and Dai Fangyin§. Fibroblast growth factor 21 prolongs lifespan and improves stress tolerance in the silkworm, Bombyx mori. Annals of Translational Medicine. 2020, 8(5): 220.

7) Song Jiangbo*, Li Zhiquan*, Tong Xiaoling, Chen Cong, Chen Min, Meng Gang, Chen Peng, Li Chunlin, Dai Fangyin^§. Genome-wide identification and characterization of Fox genes in the silkworm, Bombyx mori. Functional & Integrative Genomics. 2015, 15(5):511-522.

8) Song Jiangbo*, Xiao Li*, Zhang Zhehao, Wang Yujin, Panayiotis Kouis, Lene Juel Rasmussen, and Dai Fangyin^§. Effects of reactive oxygen species and mitochondrial dysfunction on reproductive aging. Frontiers in Cell and Developmental Biology. 2024, 12:1347286. doi: 10.3389/fcell.2024.1347286.

9) Song Jiangbo, Zhang Jianfei, Dai Fangyin^§. Advantages and limitations of silkworm as an invertebrate model in aging and lifespan research. Invited, Open Access Journal of Gerontology & Geriatric Medicine. 2018, 4(4): ID.555641.

10) Jiangbo Song*, Dongmei Tang*, Zhiquan Li*, Xiaoling Tong, Jianfei Zhang, Minjin Han, Hai Hu, Cheng Lu and Fangyin Dai^§. Variation of lifespan in multiple strains, and effects of dietary restriction and BmFoxO on lifespan in silkworm, Bombyx mori. Oncotarget, 2016, 8(5): 7294-7300.

11) Zhiquan Li*, Jiangbo Song*, Guihua Jiang, Yunzhu Shang, Yu Jiang, Jianfei Zhang, Li Xiao, Min Chen, Dongmei Tang, Xiaoling Tong, Fangyin Dai^§. Juvenile hormone suppresses the FoxO-takeout axis to shorten longevity in male silkworm. Pesticide Biochemistry and Physiology. 2023, 192: 105388.

12) Jianfei Zhang*, Zhiquan Li*, Jiangbo Song*, Lei Zhou, Xin Chen, Wen Ge, Tianyi Dong, Yuxin Luo, Ting Mao, Zheng Li, Duan Tan, Lene Juel Rasmussen, Vilhelm A. Bohr, Xiaoling Tong, Fangyin Dai^§. Salidroside promotes healthy longevity by interfering with HSP90 activity. GeroScience. 2024.46: 1641-1655. doi: 10.1007/s11357-023-00921-3.

13) Chen Cong*, Song Jiangbo*, Chen Min, Li Zhiquan, Tong Xiaoling, Hu Hai, Xiang Zhonghuai, Lu Cheng, Dai Fangyin^§. Rhodiola rosea extends lifespan and improves stress tolerance in silkworm, Bombyx mori. Biogerontology. 2016, 17: 373-381.

14) Jiang Guihua, Song Jiangbo, Hu Hai, Tong Xiaoling and Dai Fangyin^§. Evaluation of the silkworm lemon mutant as an invertebrate animal model for human sepiapterin reductase deficiency. Royal Society Open Science. 2020, 7(3): 191888.

15) Li Zheng, Song Jiangbo, Zhang Jianfei, Hao Kaige, Liu Lian, Wu Boqing, Zheng Xinyue, Xiao Bo, Tong Xiaoling, Fangyin Dai^§. Topical application of silk fibroin-based hydrogel in preventing hypertrophic scars. Colloids and Surfaces B-Biointerfaces. 2019, 186: 110735.

16)  Tao Sun, Jiangbo Song, Jingzhi Luo, Yu Jiang, Duan Tan, Lei Zhou, Wentao Wu, Minjin Han, Hai Hu, Xiaoling Tong, Cheng Lu, and Fangyin Dai^§. Dysfunction of a lepidopteran conserved gene, BmBLOC1S6, causes a translucent larval integument in the silkworm, Bombyx mori. Pest Management Science. 2025. DOI:10.1002/ps.8664.

17) 宋江波, 陈聪, 童晓玲, 代方银^§, 鲁成. 压力应答延长寿命的遗传机制. 中华医学杂志. 2013. 93(36): 2925-2927. Doi: 10.3760/cma.j.issn.0376-2491.2013.36.021.

18) 陈 聪, 宋江波, 孟 刚, 童晓玲, 代方银^§, 鲁 成. 家蚕sirtuin家族基因的鉴定及系统发生与表达芯片分析. 中国农业科学. 2014, 47(13): 2659-2670. doi: 10.3864/j.issn.0578-1752.2014.13. 018.

19) 陈 敏, 宋江波, 李知泉, 唐冬梅, 童晓玲, 代方银^§. 家蚕作为人类疾病模型与用于药物筛选的研究进展及展望. 药学学报. 2016, 51(5): 690-697. doi: 10.16438/j.0513-4870.2015-0717.