赵爱春

研究员、博士生导师

简历：

主要科研领域与方向：

蚕桑遗传工程、桑抗逆生理生化、桑食药用多元化利用、品种选育和分子生物学等蚕桑基础应用研究。

科学成就：

主要从事蚕桑遗传工程、桑抗逆生理生化、桑食药用多元化利用、品种选育和分子生物学等蚕桑基础应用研究，建立了我国第一个高效实用的家蚕转基因技术平台，是桑树基因组计划的主要参与者之一。目前任国家蚕桑产业技术体系岗位专家和功能研究室主任，先后主持了国家行业专项、国家农业产业体系和重庆市重点自然科学基金重点项目等12项国家和省部级项目；在Insect Biochemistry and Molecular Biology、FEBS Journal、Biochemistry、Scientific Reports、Plant Physiology and Biochemistry等期刊发表科研论文80余篇，SCI收录28篇；获聘重要杂志审稿人和Scientific Reports杂志基因组与遗传学领域编委；获授权专利10项（其中第一发明人4项）；获农业部科技进步二等奖1项；选育推广桑品种2个。

代表性论文/论著（*为通讯作者）

1. Boning Cao, Dingpei Long, Meng Zhang, Changying Liu, Zhonghuai Xiang, Aichun Zhao*. Molecular characterization and expression analysis of the mulberry Na+/H+ exchanger gene family. Plant Physiology and Biochemistry, 2016, 99:49–58.

2. Liu XQ, Liu CY**, Guo Q, Zhang M, Cao BN, Xiang ZH, Zhao AC*. Mulberry Transcription Factor MnDREB4A Confers Tolerance to Multiple Abiotic Stresses in Transgenic Tobacco. PLoS ONE, 2015, 10(12): e0145619.

3. X.Q. LIU, J.J. ZHU, C.J. WEI, Q. GUO, C.K. BIAN, Z.H. XIANG, and A.C. ZHAO*. Genome-wide identification and characterization of the DREB transcription factor gene family in mulberry. BIOLOGIA PLANTARUM, 2015, 59 (2): 253-265 .

4. Long D, Lu W, Zhang Y, Bi L, Xiang Z and Zhao A*. An efficient strategy for producing a stable, replaceable, highly efficient transgene expression system in silkworm, Bombyx mori. Scientific Reports, 2015, (5 March) 5 : 8802.

5. Long D, Lu W, Zhang Y, Guo Q, Xiang Z, Zhao A*. New insight into the mechanism underlying fibroin secretion in silkworm, Bombyx mori. FEBS Journal, 2015, 282(1): 89-101.

6. Wei C, Liu X, Long D, Guo Q, Fang Y, Bian C, Zhang D, Zeng Q, Xiang Z, Zhao A*. Molecular cloning and expression analysis of mulberry MAPK gene family. Plant Physiology and Biochemistry, 2014, 77: 108-116.

7. Long D, Zhao A*, Xu L, Lu W, Guo Q, Zhang Y,  Xiang Z.  In vivo site-specific integration of transgene in silkworm via PhiC31 integrase-mediated cassette exchange. Insect biochemistry and molecular biology, 2013,43(11): 997-1008.

8. Li Z**, Zhao A**, Wang X, Jin X, Li J, Yu M*. Cloning, overexpression, and functional characterization of a phytase from the genus Bacillus. Joural of Molecular Microbiology and Biotechnology, 2013, 23(3): 193-202.

9. Zhang Y, Zhao AC*, Sima YH, Lu C, Xiang Z, Nakagaki M. The molecular structures of major ampullate silk proteins of the wasp spider, Argiope bruennichi: A second blueprint for synthesizing de novo silk. Comparative Biochemistry and Physiology, Part B, 2013,164(3): 151–158.

10. Zhao A*, Zhang Y, Long D. Potential for genetic improvement of silkworm through molecular and transgenic approaches. CAB Reviews, 2013, 8(009):1-8.

11. Long DP, Zhao AC*, Chen XJ, Zhang Y, Lu WJ, Guo Q, Handler AM, Xiang ZH. FLP Recombinase-Mediated Site-Specific Recombination in Silkworm, Bombyx mori. PloS ONE, 2012, 7(6): e40150.

12. Zhao A*, Long D, Ma S, Xu L, Zhang M, Dai F, Xia Q, Lu C, Xiang Z*. Efficient strategies for changing the diapause character of silkworm eggs and for the germline transformation of diapause silkworm strains. Insect Science, 2012, 19, 172–182.

13. Zhao A*, Zhao T, Zhang Y, Xia Q, Lu C, Zhou Z, Xiang Z*, Nakagaki M. New and highly efficient expression systems for expressing selectively foreign protein in the silk glands of transgenic silkworm. Transgenic Research, 2010, 19(1):29-44.

14. Zhao AC, Zhao TF, Nakagaki K, Zhang YS, Sima YH, Miao YG, Shiomi K, Kajiura Z, Nagata Y, Takadera M, Nakagaki M*. Novel Molecular and Mechanical properties of Egg case silk from wasp spider, Argiope bruennichi. Biochemistry, 2006, 45(10): 3348-3356.

15. Zhao A, Zhao T, Sima Y, Zhang Y, Nakagaki K, Miao Y, Shiomi K, Kajiura Z, Nagata Y, Nakagaki M*. Unique Molecular Architecture of Egg Case Silk Protein in Spider, Nephila Clavata. Journal of Biochemistry，2005, 138(5): 593～604.

16. Zhao AC*, Xia QY, Lu C, Xiang ZH, Zhang YS, Nakagaki M. Insights into formation mechanism of silk fusion protein from expression of different sizes of EGFP-spider silk fusion protein in insect cells. Acta Sericologica Sinica, 2007, 33(4):581-591.

17. 赵爱春，余茂德. 果叶兼用新桑品种_嘉陵30号_及丰产栽培技术要点. 四川蚕业，2015, 1:51-52.

18. 边晨凯，龙定沛，刘雪琴，魏从进，龚加红，赵爱春*. 桑树Na+/H+逆向转运蛋白基因(MnNHX1)的克隆与耐盐力表达. 林业科学（SCIENTIA SILVAE SINICAE），2015, 51(8): 16-25.

19. 刘雪琴，丁天龙，魏从进，龙定沛，郭　庆，朱方容，何宁佳，余茂德，向仲怀，赵爱春*. 13 份桑树杂交组合F1代的耐盐性和耐旱性鉴定. 蚕业科学，2014，40（5）：0764-0773。

20. 张雨丽，张桂征，闭立辉*，祁广军，赵爱春*．转绿色荧光蛋白基因家蚕品系的纯化与综合性状改良．蚕业科学,2013, 39(2):0384-0389。

21. 李军，赵爱春**，王茜龄，张琼予，黎其友，金筱秐，李镇刚，余茂德*．三个桑树肌动蛋白基因的克隆与组织表达分析．作物学报，2011, 37(4): 641-649。

22. 李军，赵爱春**，王茜龄，祝娟娟，张琼予，金筱耘，李镇刚，鲁成，吴存容，余茂德*. 桑树肌动蛋白MaACT3启动子的克隆及农杆菌介导的瞬时表达. 中国农业科学，2012,45(4): 625-632。

23. 张阳，赵爱春*，陈雪娇，鲁成，向仲怀.一种新的单根茧丝纤维横截面积测量方法. 蚕业科学，2011，37(5)：0942-0947。

24. Xu LX, Zhao AC*, Long DP, Ta B, Xiang ZH. jC31 Integrase Mediates Genome Manipulation in higher Eukayrotes. Science of Sericulture, 2011, 37(3): 159-171.

25. 赵爱春*，龙定沛，谭兵，许龙霞，向仲怀．FLP/FRT位点特异性重组系统在高等真核生物中的研究进展．中国农业科学，2011,44(15):3252-3263。

联系地址：重庆市北碚区西南大学（南区）家蚕基因组生物学国家重点实验室，400716

电　　话：023-68251803

传　　真：023-68251128

E-mail： zhaoaichun@swu.edu.cn or zhaoaichun@hotmail.com