李春峰，研究员，博士生导师

资源昆虫高效养殖与利用全国重点实验室

Contact Us（联系方式）：
E-mail（邮件）: licf@swu.edu.cn

教育背景

2001-2008 西南大学，蚕学与系统生物学研究所，博士

1995-1998 西南农业大学，蚕学专业，硕士

1991-1995 西南农业大学，蚕学专业，学士

工作经历

2022-至今 资源昆虫高效养殖与利用全国重点实验室 研究员

2012-2013 美国密苏里大学堪萨斯分校 访问学者

2006-2022 西南大学蚕学与系统生物学研究所 副教授

2000-2006 西南农业大学蚕学与生物技术学院 讲师

1995-2000 西南农业大学蚕学与生物技术学院 助教

研究领域

病原微生物感染与防控；昆虫免疫应答

科学贡献

先后主持国家自然科学基金、重庆市自然科学基金、重庆市商务委茧丝绸发展项目、企业合作项目、中央高校科研业务费专项等课题。在Microbiology Spectrum、Insect Science、Parasit Vectors、Frontiers in Microbiology等国内外学术期刊发表研究论文90余篇。参编出版《资源昆虫及其利用》、《家蚕微孢子虫基因组生物学》、《家蚕饲养与良种繁育学》等教材及专著6部，参与《微孢子虫-机会性病原体》著作的翻译。参加完成的“家蚕微孢子虫侵染与宿主应答的分子基础”研究获得教育部高等学校科学研究优秀成果奖自然科学二等奖。

代表性论文

1) Bin Yu, Chunxia Wang, Shaogan He, Yuanke Hu, Xianzhi Meng, Junhong Wei, Tian Li, Guoqing Pan, Zeyang Zhou*, Chunfeng Li*. Construction of microsporidia-inducible GAL4/UAS-RTA system to generate resistance to Nosema bombycis in Bombyx mori. Insect Sci. 2026 Jun; 33(3): 913-928. doi: 10.1111/1744-7917.70028.

2) Renze Zhang, Shiyi Zheng, Bin Yu, Junhong Wei, Guoqing Pan, Zeyang Zhou, Chunfeng Li*. Developing Pébrine-Resistant silkworms through targeting the transmembrane protein NbTMP1 in Nosema bombycis. J Invertebr Pathol. 2026 Feb; 214:108438. doi: 10.1016/j.jip.2025.108438.

3) Shaogan He, Shiyi Zheng, Yuanke Hu, Zhonghua Yang, Honglin Zhu, Bin Yu, Junhong Wei, Guoqing Pan, Zeyang Zhou, Chunfeng Li*. The unique transmembrane protein NbTMP2 (NBO_555g0004) of Nosema bombycis contributes to host infection. J Invertebr Pathol. 2025 Jul; 211:108320. doi: 10.1016/j.jip.2025.108320.

4) Shaogan He, Shiyi Zheng, Honglin Zhu, Yuanke Hu, Bin Yu, Junhong Wei, Guoqing Pan, Zeyang Zhou, Chunfeng Li*. A novel ATP-binding cassette protein (NoboABCG1.3) plays a role in the proliferation of Nosema bombycis. Parasitol Res. 2024 Dec 19; 123(12): 413. doi: 10.1007/s00436-024-08440-6.

5) BinYu, Rong Zheng, Maofei Bian, Ting Liu, Kun Lu, Jialing Bao, Guoqing Pan, Zeyang Zhou*, Chunfeng Li*. A monoclonal antibody targeting spore wall protein 1 inhibits the proliferation of Nosema bombycis in Bombyx mori. Microbiol Spectr. 2023 Dec 12; 11(6): e0068123. doi: 10.1128/spectrum.00681-23.

6) Chaoqun Tong, Jian Luo, Chaolu Xie, Junhong Wei, Guoqing Pan, Zeyang Zhou*, Chunfeng Li*. Characterization and Biological Activities of Melanin from the Medicinal Fungi Ophiocordyceps sinensis. Int J Mol Sci. 2023 Jun 17; 24(12): 10282. doi: 10.3390/ijms241210282.

7）Bin Yu, Sichen Dong, Xiaoyu Jiang, Liang Qiao, Jie Chen, Tian Li, Guoqing Pan, Zeyang Zhou*, Chunfeng Li*. Cas9-Mediated Gene Editing Using Receptor-Mediated Ovary Transduction of Cargo (ReMOT) Control in Bombyx mori. Insects. 2023 Dec 7;14(12):932. doi: 10.3390/insects14120932.

8）Xi Sun, Bin Yu, Renze Zhang, Junhong Wei, Guoqing Pan, Chunfeng Li*, Zeyang Zhou. Generation of Resistance to Nosema bombycis (Dissociodihaplophasida: Nosematidae) by Degrading NbSWP12 Using the Ubiquitin-Proteasome Pathway in Sf9-III Cells. J Econ Entomol. 2022 Dec 14; 115(6): 2068-2074. doi: 10.1093/jee/toac145.

9）Chaoqun Tong, Junhong Wei, Guoqing Pan, Chunfeng Li*, Zeyang Zhou. Study of Pathogenesis Using Fluorescent Strain of Cordyceps farinosa Revealed Infection of Thitarodes armoricanus Larvae via Digestive Tract. Insects. 2022 Nov 10; 13(11): 1039. doi: 10.3390/insects13111039.

10) Youpeng Fan, Jialing Bao, Xiaoyu Fu, Pengfei Wu, Jinya Chen, Yan Huang, Junhong Wei, Guoqing Pan, Chunfeng Li*, Zeyang Zhou*. The NPC Families Mediate BmNPV Entry. Microbiol Spectr. 2022 Aug 31; 10(4): e0091722. doi: 10.1128/spectrum.00917-22.

11) Renze Zhang, Shiyi Zheng, Hongyun Huang, Xi Sun, Yukang Huang, Junhong Wei, Guoqing Pan, Chunfeng Li*, Zeyang Zhou. Expression of anti-NbHK single-chain antibody in fusion with NSlmb enhances the resistance to Nosema bombycis in Sf9-III cells. Bull Entomol Res. 2022 Aug; 112(4): 502-508. doi: 10.1017/S0007485321001036.

12) Shiyi Zheng, Yukang Huang, Hongyun Huang, Bin Yu, Ni Zhou, Junhong Wei, Guoqing Pan, Chunfeng Li*, Zeyang Zhou. The role of NbTMP1, a surface protein of sporoplasm, in Nosema bombycis infection. Parasit Vectors. 2021 Jan 25;14(1): 81. doi: 10.1186/s13071-021-04595-8.

13) Bin Yu, Qi Sang, Guoqing Pan, Chunfeng Li*, Zeyang Zhou. A Toll-Spätzle Pathway in the Immune Response of Bombyx mori. Insects. 2020 Sep 1;11(9):586. doi: 10.3390/insects11090586.

14) Shiyi Zheng, Yukang Huang, Jie Chen, Junhong Wei, Guoqing Pan, Chunfeng Li*, Zeyang Zhou. A specific molecular label for identifying mature Nosema bombycis spores. J Invertebr Pathol. 2020 Feb;170:107322. doi: 10.1016/j.jip.2019.107322.

15) Zhihong Li, Youpeng Fan, Junhong Wei, Xionge Mei, Qiang He, Yonghua Zhang, Tian Li, Mengxian Long, Jie Chen, Jialing Bao, Guoqing Pan, Chunfeng Li*, Zeyang Zhou*. Baculovirus Utilizes Cholesterol Transporter NIEMANN-Pick C1 for Host Cell Entry. Front Microbiol. 2019 Dec 5;10:2825. doi: 10.3389/fmicb.2019.02825.