王鑫
发布时间:2018-10-14 查看 0次   字体:[] [] []



助理研究员


简历:

2006.9 - 2010.7       成都理工大学        学士

2010.9 - 2012.6       西南大学          硕士

2012.6 - 2016.6       西南大学          博士

2016.6– 2018.7       西南大学          师资博士后

2018.8-            西南大学           助理研究员


主要科研领域与方向:

1. 蚕丝成纤机制。

2. 蚕丝性能改良。


科学成就:

从事蚕丝成纤机制及性能改良研究,已发表研究论文18篇,其中以第一作者在Biomacromolecules、Insect Biochemistry and Molecular Biology、Biochimica et Biophysica Acta、Proteomics等权威杂志发表论文7篇;获国家发明专利授权3项;主持了中国博士后科学基金一等资助、重庆市博士后研究项目特别资助项目,并参与人员参加了国家973等重大课题。


代表性论文/论著:

[1] X. Wang, P. Zhao, Y. Li, Q. Yi, S. Ma, K. Xie, H. Chen, Q. Xia, Modifying the Mechanical Properties of Silk Fiber by Genetically Disrupting the Ionic Environment for Silk Formation, Biomacromolecules, 16 (2015) 3119-3125.

[3] X. Wang, Y. Li, L. Peng, H. Chen, Q. Xia, P. Zhao, Comparative transcriptome analysis of Bombyx mori spinnerets and Filippi's glands suggests their role in silk fiber formation, Insect Biochem Mol Biol, 68 (2016) 89-99.

[3] X. Wang, Y. Li, Q. Liu, Q. Chen, Q. Xia, P. Zhao, In vivo effects of metal ions on conformation and mechanical performance of silkworm silks, Biochim Biophys Acta, 1861 (2017) 567-576.

[4] X. Wang, Y. Li, Q. Liu, Q. Xia, P. Zhao, Proteome profile of spinneret from the silkworm, Bombyx mori, Proteomics, 17 (2017) 1600301.

[5] X. Wang, Y. Li, K. Xie, Q. Yi, Q. Chen, X. Wang, H. Shen, Q. Xia, P. Zhao, Ca2+ and endoplasmic reticulum Ca2+-ATPase regulate the formation of silk fibers with favorable mechanical properties, J Insect Physiol, 73 (2015) 53-59.

[6] Y. Li, X. Wang, Y. Hou, X. Zhou, Q. Chen, C. Guo, Q. Xia, Y. Zhang, P. Zhao, Integrative Proteomics and Metabolomics Analysis of Insect Larva Brain: Novel Insights into the Molecular Mechanism of Insect Wandering Behavior, J Proteome Res, 15 (2016) 193-204.

[7] Y. Li, X. Wang, Q. Chen, Y. Hou, Q. Xia, P. Zhao, Metabolomics Analysis of the Larval Head of the Silkworm, Bombyx mori, Int J Mol Sci, 17 (2016).

[8] Q. Liu, X. Wang, X. Tan, X. Xie, Y. Li, P. Zhao, Q. Xia, A strategy for improving the mechanical properties of silk fiber by directly injection of ferric ions into silkworm, Mater Des, 146(2018):134-141.

[9] Tan X., Wang X., Liu Q., Xie X, Li Y, Li B, Li Z, Xia Q, Zhao P, Inhibition of silkworm vacuolar-type ATPase activity by its inhibitor Bafilomycin A1 induces caspase-dependent apoptosis in an embryonic cell line of silkworm, Arch Insect Biochem Physiol. 2018 Sep 24:e21507.

[10] Q. Yi, P. Zhao., X. Wang, Zou, Y., Zhong, X., Wang, C., Xiang Z., Xia, Q., Shotgun proteomic analysis of the Bombyx mori anterior silk gland: An insight into the biosynthetic fiber spinning process, Proteomics, 13 (2013) 2657-2663.

[11] Q. Chen, Z. Ma, X. Wang, Z. Li, Y. Zhang, S. Ma, P. Zhao, Q. Xia, Comparative proteomic analysis of silkworm fat body after knocking out fibroin heavy chain gene: a novel insight into cross-talk between tissues, Funct Integr Genomics, 15 (2015) 611-637.

[12] X. Tang, H. Liu, Q. Chen, X. Wang, Y. Xiong, P. Zhao, Genome-Wide Identification, Characterization and Expression Analysis of the Solute Carrier 6 Gene Family in Silkworm (Bombyx mori), Int J Mol Sci, 17 (2016).

[13] Z. Dong, P. Zhao, C. Wang, Y. Zhang, J. Chen, X. Wang, Y. Lin, Q. Xia, Comparative proteomics reveal diverse functions and dynamic changes of Bombyx mori silk proteins spun from different development stages, J Proteome Res, 12 (2013) 5213-5222.

[14] 王鑫, 李懿, 陈全梅, 衣启营, 谢康, 吴用, 赵萍, 家蚕空泡型ATP酶(V-ATPase)基因的基本信息及表达特征, 中国农业科学, 47(8) (2014) 1611-1621.

[15] 王鑫, 李懿, 陈慧芳, 周小英, 谢康, 赵萍, 利用家蚕杆状病毒表达家蚕肌质网型钙离子ATP酶蛋白, 生物工程学报, 31(3) (2015) 421-430.

[16] 谢康,王鑫,陈慧芳,李懿,宋倩茹,赵萍, 家蚕前部丝腺特异表皮蛋白Bm11721的鉴定及表达, 生物工程学报, 32(1) (2016) 64-73.

[17] 陈慧芳,王鑫,谢康,李懿,赵萍,家蚕 V型ATP酶B亚基的克隆及表达特征, 生物工程学报, 32(4) (2016) 487-496.

[18] 陈全梅, 马振刚, 王晓欢, 孙艳慧, 王鑫, 代云香, 赵萍, 家蚕感受神经膜蛋白基因SNMP1的序列分析及原核表达, 蚕业科学, 39(2) (2013) 231-239.



联系地址:重庆市北碚区西南大学(南区蚕学宫411室)家蚕基因组生物学国家重点实验室,400716

电   话: 15683676090

E-mail:xinwang@swu.edu.cn





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