韦俊宏
发布时间:2018-10-14 查看 0次   字体:[] [] []

                                             

韦俊宏

副教授

国际学术身份认证编码(ORCID)https://orcid.org/0000-0002-5748-3977.

学习与工作经历:

2005-2009   复旦大学 生物技术专业(制药方向) 理学学士

2009-2015   中国科学院微生物研究所 遗传学 理学博士

2015-2017   西南大学 家蚕基因组生物学国家重点实验室 师资博士后

2017-2022   西南大学 家蚕基因组生物学国家重点实验室 讲师

2022-至今, 西南大学 家蚕基因组生物学国家重点实验室 副教授

主要科研领域与方向:

1. 微孢子虫药物靶点和药物筛选

2. 微孢子虫遗传操作体系研究

3. 有益微生物菌种改造与资源开发

科学成就

主要从事微孢子虫药物靶点和药物筛选以及有益微生物菌种改造与资源开发的研究。主持国家自然科学基金、重庆市自然科学基金、企业合作项目、中央高校科研业务费等6项课题。先后在Applied and Environmental MicrobiologyFrontiers in MicrobiologyAntibioticsApplied Microbiology and BiotechnologyInsectsMicroorganisms等国内外学术期刊发表研究论文30余篇。参编出版专著《Microsporidia - Current Advances in Biology》和《中国养蚕学》,参与《微孢子虫-机会性病原体》著作的翻译,获授权专利2项。

代表性论文(*通讯作者)

1.         Junhong Wei, Zhihui Fei, Guoqing Pan, Louis M. Weiss, Zeyang Zhou. Current Therapy and Therapeutic Targets for Microsporidiosis. Front. Microbiol. 2022. 13:835390.

2.         Junhong Wei, Mengting Ma, Senwen Guo, Yaobo Xu, Jie Xie, Guoqing Pan, Zeyang Zhou. Characterization of Pathway-Specific Regulator NigR for High Yield Production of Nigericin in Streptomyces malaysiensis F913. Antibiotics. 2022, 11(7):938

3.         Junhong Wei, Youpeng Fan, Xiaoling Jing, Zhihui Fei, Chunfeng Li, Guoqing Pan, Jialing Bao, Zeyang Zhou. Establishment of a Novel Baculovirus–Silkworm Expression System. Microorganisms. 2022. 10, 1013

4.         Yunlin Tang, Qingyan Li, Li Xiang, Ruocheng Gu, Yanyan Wu, Yonghong Zhang, Xingrong Bai, Xiaohui Niu, Tian Li, Junhong Wei*, Guoqing Pan*, Zeyang Zhou. First Report on Megaselia scalaris Loew (Diptera: Phoridae) Infestation of the Invasive Pest Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) in China. Insects. 2021. 12(1):65.

5.         Shiyi Zheng, Yukang Huang, Jie Chen, Junhong Wei, Guoqing Pan, Chunfeng Li, Zeyang Zhou. A specific molecular label for identifying mature Nosema bombycis spores. J Invertebr Pathol. 2020. 170:107322.

6.         Zhihong Li, Youpeng Fan, Junhong Wei, Xionge Mei, Qiang He, Yonghua Zhang, Tian Li, Mengxian Long, Jie Chen, Jialing Bao, Guoqing Pan, Chunfeng Li, Zeyang Zhou. Baculovirus Utilizes Cholesterol Transporter NIEMANN-Pick C1 for Host Cell Entry. Front Microbiol. 2019. 10:2825.

7.         Junhong Wei, Lang He, Guoqing Niu. Regulation of antibiotic biosynthesis in actinomycetes: Perspectives and challenges. Synth. Syst. Biotechnol. 2018. 23;3(4):229-235

8.         Junhong Wei, Jinjin Tian, Guoqing Pan, Jie Xie, Jialing Bao, Zeyang Zhou. Development and application of a T7 RNA polymerase-dependent expression system for antibiotic production improvement in Streptomyces. Biotechnol. Lett. 2017. 39: 857-864

9.         Junhong Wei, Yuqing Tian, Guoqing Niu*, Huarong Tan*. GouR, a TetR Family Transcriptional Regulator, Coordinates the Biosynthesis and Export of Gougerotin in Streptomyces graminearus. Appl. Environ. Microbiol. 2014.80(2):714-722

10.     Lingjuan Jiang#, Junhong Wei#, Lei Li, Guoqing Niu*, Huarong Tan*. Combined gene cluster engineering and precursor feeding to improve gougerotin production in Streptomyces graminearus. Appl. Microbiol. Biotechnol. 2013. 97: 10469-10477# Contributed equally to the job

11.     Deyao Du, Yu Zhu, Junhong Wei, Yuqing Tian, Guoqing Niu * and Huarong Tan *. 2013. Improvement of gougerotin and nikkomycin production by engineering their biosynthetic gene clusters. Appl. Microbiol. Biotechnol. 2013. 97:6383-6396

12.     Guoqing Niu, Lei Li, Junhong Wei, and Huarong Tan* 2013 Cloning, heterologous expression, and characterization of the gene cluster required for gougerotin biosynthesis. Chem. Biol. 2013. 20:34–44

联系地址:重庆市北碚区天生路2号,西南大学家蚕基因组生物学国家重点实验室,400716

E-mail weijunhong@swu.edu.cn


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