陈洁
发布时间:2018-10-14 查看 0次   字体:[] [] []



博士、讲师


简历:

2005.09-2009.06  西南大学生物技术学院生物技术专业                 理学学士

2009.09-2014.06  西南大学家蚕基因组生物学国家重点实验室生物化学与分子生物学专业  理学博士

2014.07-2017.07  西南大学家蚕基因组生物学国家重点实验室畜牧学              博士后

2017.08-       西南大学家蚕基因组生物学国家重点实验室              讲师

2018.07-2018.09  澳大利亚西澳大学分子科学学院                   访问


主要科研领域与方向:

1. 微孢子虫发芽侵染机制。主要以昆虫微孢子虫为模式,研究微孢子虫特殊侵染方式——发芽侵染的分子机制。

2. 水生动物微孢子虫防控。以斑马鱼微孢子虫、对虾微孢子虫为模式,以微孢子虫-水生动物的互作机制为基础,开展水生经济动物微孢子虫病的综合研究。


科学成就:

主持国家自然科学青年基金项目、中国博士后科学基金面上项目、中央高校基本科研业务费一般项目等。参研国家“973”项目课题、国家自然科学基金重点项目、国家自然科学基金面上项目、中央高校基本科研业务费创新团队项目、重大项目等多项科研项目。近年来发表研究论文20余篇,参编著作2部,授权发明专利1项,荣获2017年教育部自然科学二等奖。


代表性论文/论著:

  1. 李治,吴正理,陈洁. 家蚕微孢子虫极管与孢壁. 周泽扬,潘国庆,李田,许金山. 家蚕微孢子虫基因组生物学. 北京:科学出版社,2014.12,ISBN 978-7-03-042451-8

  2. Jie Chen#, Wei Guo#, Xiaoqun Dang, Yukang Huang, Fangyan Liu, Xianzhi Meng, Yaoyao, Mengxian Long, Jialing Bao, Zeyang Zhou, Zhonghuai Xiang, Guoqing Pan*. Easy labeling of proliferative phase and sporogonic phase of Microsporidia Nosema bombycis in host cells. PLoS One. 2017, 12(6): e0179618

  3. Jie Chen, Lina Geng, Mengxian Long, Tian Li, Zhi Li, Donglin Yang, Chao Ma, Haijing Wu, Zhengang Ma, Chunfeng Li, Guoqing Pan, Zeyang Zhou*. Identification of a novel chitin-binding spore wall protein (NbSWP12) with a BAR-2 domain from Nosema bombycis (Microsporidia). Parasitology. 2013, 140(11): 1394-402.

  4. Yukang Huang, Jie Chen, Bin Sun, Rong Zheng, Boning Li, Zeng Li, Yaoyao Tan, Junhong Wei, Guoqing Pan, Chunfeng Li*, Zeyang Zhou*. Engineered resistance to Nosema bombycis by in vitro expression of a single-chain antibody in Sf9-III cells. PLoS One, 2018, 13(2): e0193065

  5. Yukang Huang, Shiyi Zheng, Xionge Mei, Bin Yu, Bin Sun, Boning Li, Junhong Wei, Jie Chen, Tian Li, Guoqing Pan, Zeyang Zhou*, Chunfeng Li*. A secretory hexokinase plays an active role in the proliferation of Nosema bombycis. PeerJ. 2018

  6. Donglin Yang, Lixia Pan, Pai Peng, Xiaoqun Dang, Chunfeng Li, Tian Li, Mengxian Long, Jie Chen, Yujiao Wu, Huihui Du, Bo Luo, Yue Song, Rui Tian, Jie Luo, Zeyang Zhou, Guoqing Pan*. Interaction between SWP9 and Polar Tube Proteins of the Microsporidian Nosema bombycis and Function of SWP9 as a Scaffolding Protein Contribute to Polar Tube Tethering to the Spore Wall. Infection and Immunity. 2017, 85(3): e00872-16

  7. Fangyan Liu, Qiang Ma, Xiaoqun Dang, Ying Wang, Yue Song, Xianzhi Meng, Jialing Bao, Jie Chen, Guoqing Pan, Zeyang Zhou*. Identification of a new subtilisin-like protease NbSLP2 interacting with cytoskeletal protein septin in Microsporidia Nosema bombycis. Journal of Invertebrate Pathology. 2017, 148:110-117.

  8. Zhihong Li, Guoqing Pan, Zhengang Ma, Bing Han, Bin Sun, Qi Ni, Jie Chen, Tian Li, Tongbao Liu, Mengxian Long, Chunfeng Li, Zeyang Zhou*. Comparative proteomic analysis of differentially expressed proteins in the Bombyx mori fat body during the microsporidia Nosema bombycis infection. Journal of Invertebrate Pathology. 2017, 149:36-43.

  9. Jie Xie, Ping Shu, Gary Strobel, Jie Chen, Junhong Wei, Zhonghuai Xiang, Zeyang Zhou*. Pantoea agglomerans SWg2 colonizes mulberry tissues, promotes disease protection and seedling growth. Biological Control, 2017, 113: 9-17.

  10. Jie Xie, Gary A. Strobel*, Wei-Fang Xu, Jie Chen, HuiShuang Ren, DeJun An, Brad Geary. Fungi as Architects of the Rimstone Dam in Huanglong, NSD, Sichuan, China. Micorbial Ecology, 2017, 73(1): 29-38.

  11. Donglin Yang, Guoqing Pan, Xiaoqun Dang, Yawei Shi, Chunfeng Li, Pai Peng, Bo Luo, Maofei Bian, Yue Song, Cheng Ma, Jie Chen, Zhengang Ma, Lina Geng, Zhi Li, Rui Tian, Cuifang Wei, Zeyang Zhou*. Interaction and assembly of two novel proteins in the spore wall of the microsporidian species Nosema bombycis and their roles in adherence to and infection of host cells. Infection and Immunity. 2015, 83(4):1715-31

  12. Tie Liu, Jinshan Xu, Bo Luo, Jie Chen, Zeng Li, Tian Li, Guoqing Pan, Xueyan Li, Zeyang Zhou*. Nosema sp. PM-1, a new isolate of microsporidian from infected Papilio machaon Linnaeus, based on ultrastructure and molecular identification. Acta Parasitologica. 2015, 60(2):330-6

  13. Donglin Yang, Xiaoqun Dang, Rui Tian, Mengxian Long, Chunfeng Li, Tian Li, Jie Chen, Zhi Li, Guoqing Pan, Zeyang Zhou*. Development of an approach to analyze the interaction between Nosema bombycis (microsporidia) deproteinated chitin spore coats and spore wall proteins. Journal of Invertebrate Pathology. 2014, 115:1-7.

  14. Liang Qiao, Gao Xiong, Rixin Wang, Songzhen He, Jie Chen, Xiaoling Tong, Hai Hu, Chunlin Li, Tingting Gai, Yaqun Xin, Xiaofan Liu, Bin Chen, Zhonghuai Xiang, Cheng Lu* and Fangyin Dai*. Mutation of a cuticular protein, BmorCPR2, alters larval body shape and adaptability in silkworm, Bombyx mori. Genetics. 2014, 196(4):1103-15.

  15. Zhengang Ma#, Chunfeng Li#, Guoqing Pan, Zhihong Li, Bing Han, Jinshan Xu, Xiqian Lan, Jie Chen, Donglin Yang, Quanmei Chen, Qi Sang, Xiaocun Ji, Tian Li, Mengxian Long, Zeyang Zhou*. Genome-wide transcriptional response of silkworm (Bombyx mori) to infection by the microsporidian Nosema bombycis. PLoS One. 2013, 8(12): e84137.

  16. Lipeng Lin, Guoqing Pan, Tian Li, Xiaoqun Dang, Yuanhong Deng, Cheng Ma, Jie Chen, Jie Luo, Zeyang Zhou*. The protein import pore Tom40 in the Microsporidian Nosema bombycis. Journal of Eukaryotic Microbiology. 2012, 59(3):251-257.

  17. Zhi Li, Guoqing Pan, Tian Li, Wei Huang, Jie Chen, LiNa Geng, DongLin Yang, LinLing Wang, ZeYang Zhou*. SWP5, A Novel Spore Wall Protein Interaction with Polar Tube in the Parasite Nosema bombycis (Microsporidia). Eukaryotic Cell. 2011, 11: 229-237.

  18. 龙梦娴,吴玉娇,陈洁,潘国庆,李春峰,李田,陈果,周泽扬*. 微孢子虫极管蛋白的研究进展[J]. 蚕业科学,2014,  (5) :917-923

 19. 吴玉娇, 龙梦娴*, 陈洁, 李致宏, 李治,潘国庆,李田,周泽扬. 家蚕微孢子虫极管蛋白NbPTP1的克隆、表达及验证[J]. 蚕业科学,2014, 40 (2): 258-264

  20. 马强,党晓群,王营,陈洁,刘方燕,赵丽芳,曹琛福,吕建强,潘国庆,周泽扬*. 家蚕微孢子虫经不同冻存条件处理后对家蚕胚胎细胞的侵染性变化[J]. 蚕业科学,2014 (6) :1055-1061

21. 谢洁,任慧爽,唐翠明,左伟东,陈洁,黄传书,王振江,戴凡炜,周泽扬*. 一株桑树内生细菌的鉴定和对桑椹核地杖菌的拮抗作用[J]. 蚕业科学,2015, 41(5): 0815-0824

22. 徐伟芳,王愛印,舒平,任慧爽,龙梦娴,陈洁,谢洁*. 几种常见桑树病害的识别与防治[J]. 蚕学通讯,2015, 35(2): 22-30

23. 周小伟, 龙梦娴, 陈洁, 党晓群, 李田, 潘国庆*, 周泽扬. 家蚕微孢子虫总蛋白两条大分子量主带的LC/MS-MS分析[J]. 蚕学通讯,2012,32(4):1-8.

      24. 陈洁,郭伟,潘国庆,周泽扬,向仲怀. 一种鉴别微孢子虫裂殖增殖期和孢子增殖期的双色荧光标记方法. 中国,发明专利号   ZL201610060768.7,2018.3.30


联系地址:重庆市北碚区西南大学(南区)家蚕基因组生物学国家重点实验室,400716

电  话:023-68251088

E-mail:cjswu826@163.com  jchen@swu.edu.cn



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