周泽扬
发布时间:2016-11-25 查看 0次   字体:[] [] []

 


教授、博士生导师

首批“新世纪百千万人才工程”国家级人选

农业部有特殊贡献的中青年专家

享受国务院政府特殊津贴专家

 

简历:

1978-1982

西南农业大学

本科

1987-1990

日本信州大学

硕士

1990-1993

日本大阪大学

博士

1996-2005

西南农业大学

教授、博士生导师

2005-至今

西南大学

教授、博士生导师

 

主要科研领域与方向:

主要从事微生物学及家蚕分子生物学研究,目前从事领域有:

(1) 家蚕微孢子虫的功能基因组学研究。运用微孢子虫的基因组数据,对微孢子虫重要的生物学问题如侵染、增殖、垂直传播,病原与宿主的相互作用等方面进行深入研究。

(2)蚕桑病原微生物检测与防控。以蚕桑重要病原微生物为对象,以解决蚕业重要问题、解放生产力为目标导向,建立检测方法和检测标准,研发快速、特异的检测产品。基于病原微生物的基础研究,开展抗性素材创建、生物防控等研究以解决生产实际问题。

(3)微生物资源及次生代谢研究。主要采用微生物学方法、宏基因组学方法和生物化学方法,从不同生境筛选、纯化、改造微生物,用于农林病虫害的生防研究。


科学成就:

现任重庆师范大学校长、西南大学家蚕基因组生物学国家重点实验室副主任,重庆市科协副主席、重庆市微生物学会副理事长。主要从事微生物学、家蚕病原微生物功能基因组学和家蚕分子生物学研究,推动开展了家蚕基因组计划,组织完成了家蚕病原性微孢子虫基因组的测序分析,主持开展了蚕桑病原微生物抗病、检测,功能基因组学、寄生虫与宿主互作关系以及资源微生物开发利用等研究。近年来先后主持“863”项目、 “973”项目子课题、国家转基因植物专项、国家自然科学基金重点项目等20余项重大课题,先后在Science、BMC Genomics、Proteomics、Eukaryotic Cell、Parasitology等国内外学术杂志发表研究论文130余篇。获国家自然科学二等奖、重庆市自然科学一等奖、第四届中国科协西部开发突出贡献奖、“全国五一劳动奖章”等奖励。已培养毕业硕博士研究生90余人,指导的博士毕业生中一名获评2010年度“全国百篇优秀博士论文”,多名毕业生获评重庆市优秀毕业论文。

 

代表性论文/论著:

周泽扬,潘国庆,许金山,李田等,家蚕微孢子虫基因组学,2014,科学出版社

[1]. Han B , Zhou K, Li Z, Sun B, Ni Q, Meng X, Pan G, Li C, Long M, Li T, Zhou C, Li W, Zhou Z. Characterization of the First Fungal Glycosyl Hydrolase Family 19 Chitinase (NbchiA) from Nosema bombycis (Nb). J Eukaryot Microbiol. 2016, 63(1):37-45.

[2]. Pan Q, Wang L, Dang X, Ma Z, Zhang X, Chen S, Zhou Z, Xu J. Bacterium-Expressed dsRNA Downregulates Microsporidia Nosema bombycis Gene Expression. J Eukaryot Microbiol, 2016 Jul. doi: 10.1111/jeu. 12346. [Epub ahead of print]

[3]. Li Y, Tao M, Ma F, Pan G, Zhou Z, Wu Z. A monoclonal antibody that tracks endospore formation in the microsporidium Nosema bombycis. PLoS One. 2015, 10(3): e0121884.

[4]. Xie J, Strobel GA, Feng T, Ren H, Mends MT, Zhou Z, Geary B. An endophytic Coniochaeta velutina producing broad spectrum antimycotics. J Microbiol. 2015, 53(6): 390–397.

[5]. Zhao W, Hao Y, Wang L, Zhou Z, Li Z. Development of a strategy for the identification of surface proteins in the pathogenic microsporidian Nosema bombycis. Parasitology. 2015, 142(07): 1-14.

[6]. He Q, Ma Z, Dang X, Xu J, Zhou Z. Identification, Diversity and Evolution of MITEs in the Genomes of Microsporidian Nosema Parasites. PLoS One. 2015, 10(4): e0123170.

[7]. Yang D, Pan G, Dang X, Shi Y, Li C, Peng P, Luo B, Bian M, Song Y, Ma C, Chen J, Ma Z, Geng L, Li Z, Tian R, Wei C, Zhou Z. Interaction and assembly of two novel proteins in the spore wall of the microsporidian species Nosema bombycis and their roles in adherence to and infection of host cells. Infect Immun. 2015, 83(4): 1715-1731.

[8]. Wang Ling, He Chengmin, Dang Xiaoqun, Xu Jinshan, Zhou Zeyang. Identification,Evolutionary and Transcriptional Activity Analyses of a Dicer-like Gene in Microsporidium Nosema bombycis. Science of Sericulture. 2015,41(1): 0064-0071. (In Chinese)

[9]. ZHANG Suzhen, XU Jinshan, MA Zhengang, ZHOU Zeyang. stablishment and Application of a Method Suitable for Extracting Midgut Total Proteins from Honeybe Apis melifera ligustica. J Chongqing Normal University (Natural Science). 2015, 32(4): 49-53. (In Chinese)

[10]. Liu T, Xu J, Luo B, Chen J, Li Z, Li T, Pan G, Li X, Zhou Z. Nosema sp. PM-1, a new isolate of microsporidian from infected Papilio machaon Linnaeus, based on ultrastructure and molecular identification. Acta Parasitol. 2015, 60(2): 330-336.

[11]. Wang Y, Dang X, Luo B, Li C, Long M, Li T, Li Z, Pan G, Zhou Z. Characterization of a novel otubain-like protease with deubiquitination activity from Nosema bombycis (Microsporidia). Parasitol Res. 2015. [Epub ahead of print]

[12]. He Q, Liu SL, Ma ZG, Zhang YY, Vossbrinck CR, Xu JS, Zhou ZY. Comparative genomics of three geographical strains reveals genetic diversity in Antheraea pernyi nucleopolyhedroviruses. Acta Entomol Sinica. 2015, 58(5):535-54.

[13]. Wang Y, Dang X, Ma Q, Liu F, Pan G, Li T, Zhou Z.Characterization of a novel spore wall protein NbSWP16 with proline-rich tandem repeats from Nosema bombycis (microsporidia). Parasitology. 2014, 3:1-9. [PubMed]

[14]. Xiang H, Zhang R, De Koeyer D, Pan G, Li T, Liu T, Zhou Z. New evidence on the relationship between Microsporidia and Fungi: a genome-wide analysis by DarkHorse software. Can J Microbiol. 2014 Jul 14:1-12. [PubMed]

[15]. Bo Luo, Handeng Liu, Guoqing Pan, Tian Li, Zeng Li, Xiaoqun Dang, Tie Liu, Zeyang Zhou. Morphological and molecular studies of Vairimorpha necatrix BM, a new strain of the microsporidium V. necatrix (microsporidia, burenellidae) recorded in the silkworm, Bombyx mori. Exp Parasitol. 2014, pii: S0014-4894(14)00115-5. doi: 10.1016/j.exppara.2014.05.001. [PubMed]

[16]. LIU Tie, XU Jin⁃Shan, LI Tian, PAN Guo⁃Qing, HE Qiang, LI Xue⁃Ya, ZHOU Ze⁃Yang. Identification and Phylogenetic Analysis of MITE Transposons in a

Microsporidia Isolate from Papilio machaon Linnaeus. Science of Sericulture. 2014, 40(1): 0052-0058. (In Chinese)

[17]. Zhengang Ma, Chunfeng Li, Guoqing Pan, Zhihong Li, Bing Han, Jinshan Xu, Xiqian Lan, Jie Chen, Donglin Yang, Quanmei Chen, Qi Sang, Xiaocun Ji, Tian Li, Mengxian Long, Zeyang Zhou. Genome-wide transcriptional response of silkworm (Bombyx mori) to infection by the microsporidian Nosema bombycis. PloS ONE. 2013, 8(12): e84137. [PubMed]

[18]. Chen J, Geng L, Long M, Li T, Li Z, Yang D, Ma C, Wu H, Ma Z, Li C, Pan G, Zhou Z. Identification of a novel chitin-binding spore wall protein (NbSWP12) with a BAR-2 domain from Nosema bombycis (microsporidia). Parasitology. 2013, 140(11): 1394-402. [PubMed]

[19]. Yang D, Dang X, Tian R, Long M, Li C, Li T, Chen J, Li Z, Pan G, Zhou Z. Development of an approach to analyze the interaction between Nosema bombycis (microsporidia) deproteinated chitin spore coats and spore wall proteins. J Invertebr Pathol. 2013, pii:S0022-2011(13)00149-3. [PubMed]

[20]. Pan G, Xu J, Li T, Zhou Z et al. Comparative genomics of parasitic silkworm microsporidia reveal an association between genome expansion and host adaptation. BMC Genomics, 2013, 14: 186. [PubMed]

[21]. Dang X, Pan G, Li T, Zhou Z, et al. Characterization of a subtilisin-like protease with apical localization from microsporidian Nosema bombycis. J Invertebr Pathol, 2013, 112(2): 166-174. [PubMed]

[22]. Liu H, Pan G, Dang X, Li T, Zhou Z. et al. Characterization of active ribosomal RNA harboring MITEs insertion in microsporidian Nosema bombycis genome. Parasitol Res, 2013, 112(3):1011-1020. [PubMed]

[23]. GENG Li-Na, WU Hai-Jing, LIU Ting, TIAN Rui, LI Tian, PAN Guo-Qing, ZHOU Ze-Yang. Two-dimensional Electrophoresis Analysis of Nosema bombycis Spore Coat Proteins Prepared by Germination Method and Glas Beads Breaking Method. Science of Sericulture. 2013, 39(5): 0928-0934. [In Chinese]

[24]. LI Zhi-Hong, MA Zhen-Gang, LI Wan-Jun, LIU Jun, HAN Bing, LI Tian, PAN Guo-Qing, LI Chun-Feng, ZHOU Ze-Yang. Analysis and Identification of the Differentially Expressed Hemolymph Proteins of Silkworm (Bombyx mori) Infected by Nosema bombycis. Science of Sericulture. 2013, 39(5): 0921-0927. [In Chinese]

[25]. LUO Jie, DENG Yuan-Hong, HUANG Wei, LI Tian, YANG Qiong, YIN Mei, PAN Guo-Qing, LI Chun-Feng, ZHOU Ze-Yang. Sequence Analysis and Subcellular Localization of a Novel Nosema bombycis Gene in Saccharomyces cerevisiae Cells. Science of Sericulture. 2013, 39(2): 0302-0309. [In Chinese]

[26]. LI Tian, QI Xiao-Ran, TAO Mei-Lin, ZHOU Ze-Yang, et al. Comparative Genomics Analysis of Secreted Proteins from Four Microsporidia. Science of Sericulture, 2013, 39(3):0527-0536. [In Chinese]

[27]. LI Tian, LIU Xian-Lin, HAN Bing, ZHOU Ze-Yang, et al. Predicting and Analyzing Whole-genome Secreted Proteins of Microsporidian Nosema bombycis. Science of Sericulture, 2013, 39(2): 0295-0301. [In Chinese]

[28]. Lin L, Pan G, Li T, Zhou Z, et al. The protein import pore Tom40 in the Microsporidian Nosema bombycis. J Eukaryot Microbiol, 20012, 59(3):251-257. [PubMed]

[29]. Liu H, Pan G, Li T, Zhou Z, et al. Ultrastructure, chromosomal karyotype, and molecular phylogeny of a new isolate of microsporidian Vairimorpha sp. BM (Microsporidia, Nosematidae) from Bombyx mori in China. Parasitol Res, 2012, 110(1): 205-210. [PubMed]

[30]. Li Z, Pan G, Li T, Zeyang Zhou, et al. SWP5, A Novel Spore Wall Protein Interaction with Polar Tube in the Parasite Nosema bombycis (Microsporidia). Eukaryotic Cell, 2012, 11: 229-237. [PubMed]

[31]. Xu J, Wang L, Tang F, Zhou Z, et al. The nuclear apparatus and chromosomal DNA of the microsporidian Nosema antheraeae. J Eukaryot Microbiol, 2011, 58(2): 178-180. [PubMed]

[32]. DENG Yuan-Hong, LI Neng-Zhang, LIN Li-Peng, ZHOU Ze-Yang, et al. The N-terminal Coding Sequence of Cell Division Cycle Protein of Nosema bombycis has Promoter Activity in Saccharomyces cerevisiae. Science of Sericulture, 2011, 37(4): 0688-0694. [In Chinese]

[33]. Xiang H, Pan G, Zhang R, Zhou Z, et al. Natural selection maintains the transcribed LTR retrotransposons in Nosema bombycis. J Genet Genomics, 2010, 37: 305-314. [PubMed]

[34]. Xiang H, Pan G, Vossbrinck CR, Zhou Z, et al. A tandem duplication of manganese superoxide dismutase in Nosema bombycis and its evolutionary origins. J Mol Evol, 2010, 71(5-6): 401-414. [PubMed]

[35]. Xu J, Wang M, Zhang X, Zhou Z, et al. Identification of NbME MITE families: potential molecular markers in the microsporidia Nosema bombycis. J Invertebr Pathol, 2010, 103(1): 48-52. [PubMed]

[36]. Li Y, Wu Z, Pan G, Zhou Z, et al. Identification of a novel spore wall protein (SWP26) from microsporidia Nosema bombycis.Int J Parasitol, 2009, 39(4): 391-398. [PubMed]

[37]. Wu Z, Li Y, Pan G, Zhou Z, Xiang Z. SWP25, a novel protein associated with the Nosema bombycis endospore. J Eukaryot Microbiol, 2009, 56(2):113-118. [PubMed]

[38]. Tian Li, Xiaoqun Dang, Guoqing Pan, Zeyang Zhou, et al. Mitochondrial Pyruvate Dehydrogenase E1 of Nosema bombycis – a Marker in Microsporidian Evolution. Current Zoology, 2009, 55: 423-429. [PDF]

[39]. LI Tian, PAN Guo-Qing, DANG Xiao-Qun, ZHOU Ze-Yang. cDNA Library Construction and EST Analysis of Bombyx mori Silk Gland Heavily Infected by Nosema bombycis. Science of Sericulture, 2009, 35(2): 320-327. [In Chinese]

[40]. Tao M, Pan G, Hu H, Zhou Z. Identification of a new serpin gene (NbSPN106) from Nosema bombycis. Wei Sheng Wu Xue Bao, 2009, 49(6): 726-32. [In Chinese]

[41]. Wu Z, Li Y, Pan G, Zhou Z, et al. Proteomic analysis of spore wall proteins and identification of two spore wall proteins from Nosema bombycis (Microsporidia). Proteomics, 2008, 8(12):2447-2461. [PubMed]

[42]. Liu H, Pan G, Song S, Zhou Z, et al. Multiple rDNA units distributed on all chromosomes of Nosema bombycis. J Invertebr Pathol, 2008, 99(2):235-238. [PubMed]

[43]. Wu Z, Li Y, Pan G, Zhou Z, et al. A complete Sec61 complex in Nosema bombycis and its comparative genomics analyses. J Eukaryot Microbiol, 2007, 54(4): 379-380. [PubMed]

[44]. Xu J, Pan G, Fang L, Zhou Z, et al. The varying microsporidian genome: existence of long-terminal repeat retrotransposon in domesticated silkworm parasite Nosema bombycis. Int J Parasitol, 2006, 36(9): 1049-1056. [PubMed]

 

 

联系地址:重庆市北碚区西南大学(南区)家蚕基因组生物学国家重点实验室,400716

电    话: 023-68251088

传    真: 023-68251128

E-mail   :zyzhou@swu.edu.cn


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