潘敏慧
发布时间:2016-11-25 查看 0次   字体:[] [] []

博士,教授,博士生导师 ,国家蚕桑产业技术体系岗位科学家。

 

简历:

2007-

西南大学

教授

2002-2007

西南大学

副教授

1997-2002

西南农业大学

讲师

1997-1998

日本信州大学纤维学部留学


2002-2005

西南农业大学

博士研究生

1997-2001

西南农业大学

硕士研究生

1988-1992

西南农业大学

本科生

 

主要科研领域与方向:

家蚕细胞凋亡与周期调控、家蚕病理学与蚕病防控


科学成就:

主要从事家蚕病原微生物分类、分子病理学和细胞生物学等领域的研究。发现和鉴定了一种新的家蚕病原微孢子虫SCM8和一种新型家蚕浓核病毒BmDNV-6;构建了家蚕细胞生物学研究平台,建立了多个家蚕胚胎细胞系和家蚕卵巢细胞系。先后主持国家自然科学基金、国家支撑计划、国家蚕桑产业技术体系和省部级项目9项,主研“863”、“973”、“国家攻关计划”和省部级项目17项,在国内外重要学术杂志上发表研究论文100余篇,授权专利3项。

 

代表性论文/论著:

[1] Dong ZQ, Chen TT, Zhang J, Hu N, Cao MY, Dong FF, Jiang YM, Chen P, Lu C*, Pan MH*. Establishment of a highly efficient virus-inducible CRISPR/Cas9 system in insect cells. Antiviral Research.2016,130:50-57. (*,co-corresponding author)

[2] Cao MY, Kuang XX, Li HQ, Lei XJ, Xiao WF, Dong ZQ, Zhang J, Hu N, Chen TT, Lu C*, Pan MH*. Screening and optimization of an efficient Bombyx mori nucleopolyhedrovirus inducible promote. Journal of Biotechnology.2016 May 28. [Epub ahead of print] (*,co-corresponding author)

[3] Liu TH, Dong XL, Pan CX, Du GY, Wu YF, Yang JG, Chen P, Lu C*, Pan MH*. A newly discovered member of the Atlastin family, BmAtlastin-n, has an antiviral effect against BmNPV in Bombyx mori. SCIENTIFIC REPORTS. 2016 Jun 29;6:28946. (*,co-corresponding author)

[4] Wang L, Song J, Bao XY, Chen P, Yi HS, Pan MH*, Lu C*. BmDredd is an initiator caspase and plays a role in caspase-dependent apoptotic pathway in the silkworm, Bombyx mori. Gene. 2016 Jun 10. [Epub ahead of print] (*,co-corresponding author)

[5] Li YF,Chen XY,Tang XF,Zhang CD,Wang L,Chen P,Pan MH*,Lu C*. DNA synthesis during endomitosis is stimulated by insulin PI3K/Akt and TOR signaling pathway in silk gland cells of the silkworm, Bombyx mori. International Journal of Molecular Sciences. 2015, 16, 6266-6280. (*,co-corresponding author)

[6] Chen XY,Liu J,Zhang CD,Li YF,Liu TH,Hu YF,,Yu QY,Lu C*,Pan MH*. The silkworm GSTe4 is sensitive to phoxim and protects HEK293 cells against UV-induced cell apoptosis. Bulletin of Entomological Research. 2015 ,105(4):399-407. (*,co-corresponding author)

[7] Li YF,Chen XY,Zhang CD,Tang XF,Wang L,Liu TH,Pan MH*,Lu C*. Effects of starvation and hormones on DNA synthesis in silk gland cells of the silkworm, Bombyx mori. Insect Science.2015 Jan 2. [Epub ahead of print] (*,co-corresponding author)

[8] Feng ZY,Pan C,Liu M,Tian ZQ,Chen XM,Kuang XX,Lu C,Pan MH*. Establishment and Gene Expression Characteristics of the Silk Gland Cell Line BmSG-SWU1 of Bombyx mori (Lepidoptera: Bombycidae). Ann. Entomol. Soc. Am. 2014,107(99):1018-1026. (*,corresponding author)

[9] Zhang J, Chen XM, Zhang CD, He Q, Dong ZQ, Cao MY, Dong XL, Pan CX, Lu C*, Pan MH*. Differential susceptibilities to BmNPV infection of two cell lines derived from a single silkworm ovarian tissue. PLoS One.2014,9(9) , e105986. (*,co-corresponding author)

[10] Pan C, Hu YF, Yi HS, Song J, Wang L, Pan MH*, Lu C*. Role of Bmbuffy in hydroxycamptothecin-induced apoptosis in BmN-SWU1cells of silkworm, Bombyx mori. Biochem Biophys Res Commun. 2014,447( 2):237-24. (*,co-corresponding author)

[11] Zhang J, Dong ZQ, He Q,Chen XM, Cao MY, Li HQ, Xiao WF,Lu C*, Pan MH*.  Identification of a novel nuclear localization signal of baculovirus late expression factor 11. Virus Research.2014,184:111–119. (*,co-corresponding author)

[12] Dong ZQ, Zhang J, Chen XM,He Q, Cao MY,Wang L,Li HQ, Dong XL, Pan CX, Lu C*,Pan MH*. Bombyx mori nucleopolyhedrovirus ORF79 is a per os infectivity factor ssociated with the PIFs complex. Virus Research.2014,184:62–70. (*,co-corresponding author)

[13] Yi HS, Pan CX, Pan C, Song J, Hu YF, Wang L, Pan MH*, Lu C*. BmICE-2 is a novel pro-apoptotic caspase involved in apoptosis in the silkworm, Bombyx mori. Biochem Biophys Res Commun. 2014,445(1):100-6. (*,co-corresponding author)

[14] Zhang J, He Q, Zhang CD, Chen XY, Chen XM, Dong ZQ, Li N, Kuang XX, Cao MY, Lu C*, Pan MH*. Inhibition of BmNPV replication in silkworm cells using inducible and regulated artificial microRNA precursors targeting the essential viral gene lef-11. Antiviral Res. 2014 ,104 :143–152. (*,co-corresponding author)

[15] Wang W, Huang MH, Dong XL, Chai CL, Pan CX, Tang H, Chen YH, Dai FY, Pan MH*,Lu C*. Combined Effect of Cameo2 and CBP on the Cellular Uptake of Lutein in the Silkworm, Bombyx mori. PLoS One. 2014,9(1):e86594. (*,co-corresponding author)

[16] Pan MH, Hong KL, Chen XY, Pan C, Chen XM, Kuang XX, Lu C. BmCyclin B3 are required for cell cycle progression of silkworm, Bombyx mori. Sci China Life Sci. 2013,56(4):360-5. (*,corresponding author)

[17] Zhang JY,Pan C, Yi HS, Xu W, Hu YF, Song J, Pan MH*, Lu C*  Caspase family member BmDronc from the BmE cell in Bombyx mori. Ann. Entomol. Soc. Am. 2013,106(2): 265-272(*,co-corresponding author)

[18] Pan MH, Du J, Zhang JY, Huang MH, Li T, Cui HJ, Lu C*   Cloning of the Flap Endonuclease-1 Gene in Bombyx mori and Identification of an Antiapoptotic Function. DNA and Cell Biology. 2011,30(10):763-70. (*,corresponding author)

[19] Zhang CD*, Pan MH*, Tan J, Li FF, Zhang J, Wang TT, Lu C. Characteristics and evolution of the PUF gene familyies in Bombyx mori and 27 other species. Mol Biol Rep. 2012,39(1):675-83. (*, co-first author).

[20] Zhang JY*, Pan MH*, Sun ZY, Huang SJ, Yu ZS, Liu D, Zhao DH, Lu C§. The genomic underpinnings of apoptosis in the silkworm, Bombyx mori. BMC Genomics. 2010;11(1):611. (*, co-first author).

[21] Pan MH, Cai XJ, Liu M, Lv J, Tang H, Tan J, Lu C*   Establishment and Characterization of an Ovarian Cell Line of the Silkworm, Bombyx mori. Tissue Cell ,2010, 42:42-46. (*,corresponding author)

[22] Pan MH, Wang XY, Chai CL, Zhang CD, Lu C, Xiang ZH.*,Zhong-Huai Xiang  Identification and function of Abdominal-A in the Silkworm, Bombyx mori. Insect Molecular Biology,2009,18(2):155–160. (*,corresponding author)

[23] Pan MH, Xiao SQ, Li N,Lu C*, Xiang ZH  Histophysiological Character of a Densovirus-like from Silkworm,Bmbyx mori. Acta Entomologica Sinica,2009,52(1):46-51. (*,corresponding author)

[24] Pan MH, Yu QY, Xia YL, Dai FY, Liu YQ,Lu C*, Zhang Z,Xiang ZH. Characterization of the mitochondrial genome of the Chinese wild mulberry silkworm, Bombyx mandarina (Lepidoptera: Bombycidae). Sci China ser C-Life Sci,2008,51(8):693-701. (*,corresponding author)

[25] Pan MH, Xiao SQ, Chen M, Hong XJ, Lu C.*  Establishment and characterization of two enbryonic cell lines of Bombyx mori. In Vitro Cell.Dev.Biol-Animal, 2007, 43:101-104. (*,corresponding author)

 

联系地址:重庆市北碚区西南大学(南区)家蚕基因组生物学国家重点实验室,400716

电    话: 023-68250076

传    真:

E-mail:pmh047@126.com


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