副研究员、硕士生导师

简历：

1999-2003     西南农业大学                    本科生 

2003-2008     西南农业大学（西南大学）              博士生（硕博连读）

2008-2012     重庆大学农学及生命科学研究院            讲师 

2014-2016     康奈尔大学BTI研究所访问学者

2012-       家蚕基因组生物学国家重点实验室（西南大学）     副研究员

主要科研领域与方向：

基于昆虫-植物互作机制的家蚕营养利用及害虫防控研究；昆虫抗病抗逆分子机制研究；动植物遗传工程。

科学成就：

（1）创建了基于转基因RNAi和增量表达抗病毒蛋白的家蚕抗病分子育种平台技术体系，制作获得了对家蚕核型多角体病毒（BmNPV）具有增强抗性的转基因家蚕素材数个。

（2）作为家蚕基因组研究团队成员，参加了家蚕基因组计划及家蚕全基因组芯片的研制。参加了“十一五”、“十二五”家蚕“973”、“863”、“948”项目及国家自然科学基金及省部级等项目数项；主持国家自然科学基金、重庆市基础科学与前沿技术研究项目、中央高校科研业务费等科研项目10余项。近年来已在国内外高水平期刊发表论文30余篇，参与编写专著2部；获得专利授权6 项，申请专利2项。

代表性论文/论著：

1. Yan Hao, Liu qingsong, Wen feng, Bai bingchuan, Wen Yuchan, Chen Wenwen, Lu Wei, Lin Ying, Xia Qingyou, Wang genhong #(Corresponding author) (2020). Characterization and potential application of an α-amylase (BmAmy1) selected during silkworm domestication. International Journal of Biological Macromolecules, S0141-8130(20)34991-6.

2. Li Yueyue, Zhao min, Chen Wenwen, Du Hongyi, Xie Xiaodong, Wang Daibin, Dai Ya, Xia Qingyou, Wang Genhong# (Corresponding author) (2020). Comparative transcriptomic analysis reveals that multiple hormone signal transduction and carbohydrate metabolic pathways are affected by Bacillus cereus in Nicotiana tabacum. Genomics, 112, 4254–4267

3. Chen Yanfei, Bai Bingchuan, Yan Hao, Wen Feng, Qin Daoyuan, Jander Georg, Xia Qingyou, Wang Genhong#(Corresponding author) (2019). Systemic disruption of the homeostasis of transfer RNA isopentenyltransferase causes growth and development abnormalities in Bombyx mori. Insect molecular biology, 28(3), 380–391.

4. Li Yueyue, Bai Bingchuan, Wen Feng, Zhao Min, Xia Qingyou, Yang Da-Hai*, and Genhong Wang*(Corresponding author) (2019). Genome-Wide Identification and Expression Analysis of HD-ZIP I Gene Subfamily in Nicotiana tabacum. Genes, 10(8): 575.

5. Wang Genhong, Wang Pei, Gao Yulong, Li Yueyue, Wu Lei, Gao Junping, Zhao Min, Xia Qingyou (2018). Isolation and functional characterization of a novel FLOWERING LOCUS T homolog (NtFT5) in Nicotiana tabacum. Journal of plant physiology. 2018;231:393-401.

6.Wang Genhong, Chen Yanfei, Zhang Xiaoying, Bai Bingchuan, Yan Hao, Qin Daoyuan, Xia Qingyou (2018). Selection of reference genes for tissue/organ samples on day 3 fifth-instar larvae in silkworm, Bombyx mori. Arch Insect Biochem Physiol 98(2), e21458.

7.Wu Lei, Zhang Xiaoying, Xu Bingxin, Li Yueyue, Jia Ling, Wang Rengang, Ren Xueliang, Wang Genhong#(Corresponding author), Xia Qingyou (2018). Identification and expression analysis of EDR1-like genes in tobacco (Nicotiana tabacum) in response to Golovinomyces orontii. PeerJ 6, e5244.

8. Genhong Wang, Liang Jiang, Li Zhu, Ting-Cai Cheng, Wei-Huan Niu, Ya-Fei Yan and Qing-You Xia.(2013). “Characterization of Argonaute family members in the silkworm, Bombyx mori.” Insect Science. 00:1-14.

9. Genhong Wang, Chun Liu, Xing-fu Zha, Jie Chen, Liang Jiang and Q.-y. Xia. (2008). "Cathepsin B protease is required for metamorphism in silkworm, Bombyx mori." Insect Science 15: 201-208.

10. Genhong Wang, Qing-You Xia, Dao-Jun Cheng, Jun Duan, Ping Zhao, Jie Chen and Z. Li. (2008). "Reference genes identified in the silkworm Bombyx mori during metamorphism based on oligonucleotide microarray and confirmed by qRT-PCR." Insect Science 15: 405-413.

11. Junping Gao, Genhong Wang＃ (Co-first author), Sanyuan Ma, Xiaodong Xie, Xiangwei Wu, Xingtan Zhang, Yuqian Wu, Ping Zhao and Qingyou Xia (2015). CRISPR/Cas9-mediated targeted mutagenesis in Nicotiana tabacum. Plant Mol Biol, 87, 99-110.

12. Xiaodong Xie, Genhong Wang＃ (Co-first author), Ling Yang, Tingcai Cheng, Junping Gao, Yuqian Wu and Qingyou Xia (2015) Cloning and characterization of a novel Nicotiana tabacum ABC transporter involved in shoot branching. Physiol Plant, 153, 299-306.

13. Qingyou Xia, Daojun Cheng, Jun Duan, Genhong Wang, Tingcai Cheng, Xingfu Zha, Chun Liu, Ping Zhao, Fangyin Dai, Ze Zhang, Ningjia He, Liang Zhang and Zhonghuai Xiang (2007). "Microarray-based gene expression profiles in multiple tissues of the domesticated silkworm, Bombyx mori." Genome Biol 8(8): R162.

14. Xingtan Zhang, Mengyun Nie, Qian Zhao, Yuqian Wu, Genhong Wang and Qingyou Xia (2015) Genome-wide patterns of genetic variation among silkworms. Mol Genet Genomics, 290, 1575-87.

15. Xingtan Zhang, Genhong Wang, Junping Gao, Mengyu Nie, Wenshan Liu and Qingyou Xia (2016) Functional analysis of NtMPK2 uncovers its positive role in response to Pseudomonas syringae pv. tomato DC3000 in tobacco. Plant Mol Biol, 90, 19-31.

16. Xiaodong Xie, Tingcai Cheng, Genhong Wang, Jun Duan, Weihuan Niu and Qingyou Xia (2012) Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in the silkworm, Bombyx mori. Mol Biol Rep, 39, 7281-91.

17. Zhao, P., Genhong Wang, Z. M. Dong, J. Duan, P. Z. Xu, T. C. Cheng, Z. H. Xiang and Q. Y. Xia (2010). "Genome-wide identification and expression analysis of serine proteases and homologs in the silkworm Bombyx mori." BMC Genomics 11: 405.

18. Jiang, L., G. Wang, T. Cheng, Q. Yang, S. Jin, G. Lu, F. Wu, Y. Xiao, H. Xu and Q. Xia (2012). "Resistance to Bombyx mori nucleopolyhedrovirus via overexpression of an endogenous antiviral gene in transgenic silkworms." Arch Virol.

19. Zhao, P., Z. Dong, J. Duan, G. Wang, L. Wang, Y. Li, Z. Xiang and Q. Xia (2012). "Genome-wide identification and immune response analysis of serine protease inhibitor genes in the silkworm, Bombyx mori." PLoS One 7(2): e31168.

20. Jiang, L., T. Cheng, P. Zhao, Q. Yang, G. Wang, S. Jin, P. Lin, Y. Xiao & Q. Xia (2012) Resistance to BmNPV via overexpression of an exogenous gene controlled by an inducible promoter and enhancer in transgenic silkworm, Bombyx mori. PLoS One, 7, e41838.

21. Jiang, L., P. Zhao, G. Wang, T. Cheng, Q. Yang, S. Jin, P. Lin, Y. Xiao, Q. Sun & Q. Xia (2012) Comparison of factors that may affect the inhibitory efficacy of transgenic RNAi targeting of baculoviral genes in silkworm, Bombyx mori. Antiviral Res, 97, 255-263.

22. Jiang, L., P. Zhao, T. Cheng, Q. Sun, Z. Peng, Y. Dang, X. Wu, G. Wang, S. Jin, P. Lin & Q. Xia (2013) A transgenic animal with antiviral properties that might inhibit multiple stages of infection. Antiviral Res, 98, 171-3.

23. Xingtan Zhang, Tingcai Cheng, Genhong Wang, Yafei Yan, Qingyou Xia(2012). Cloning and evolutionary analysis of tobacco MAPK gene family. Mol Biol Rep. DOI 10.1007/s11033-012-2184-9.

24. The International Silkworm Genome, C. (2008) The genome of a lepidopteran model insect, the silkworm Bombyx mori. Insect Biochem Mol Biol, 38, 1036-45. (the 28th author in the Chinese group).

25. Cheng, D., Q. Xia, J. Duan, L. Wei, C. Huang, Z. Li, G. Wang and Z. Xiang (2008). "Nuclear receptors in Bombyx mori: Insights into genomic structure and developmental expression." Insect Biochem Mol Biol 38(12): 1130-7.

26. 王根洪, 祝慧敏, 罗会松, 王轲轲, 杨小波, 蒋亮, 夏庆友 (2011). "细菌表达dsRNA介导的家蚕FTZ-F1基因的RNA干扰." 昆虫学报 54(5): 596-601.

27. 王根洪, 刘春, 杨远萍, 吴雪峰, 夏庆友 (2005). "siRNA介导的家蚕ABC转运蛋白相关基因的干涉研究." 蚕业科学(2): 117-120,i001.

28. 艾均文, 王根洪, 李艳红, 余泉友, 张学松, 朱勇, 向仲怀. (2008). "家蚕P450基因CYP18A1的克隆、序列分析及其表达谱研究." 昆虫学报 3: 237-245.

29.王振兴, 王璞, 姚玲, 曾智东, 徐汉福, 段军, 王根洪, 夏庆友 (2006). "家蚕细胞凋亡相关基因BmlCAD的克隆、序列和功能分析及其在精巢中特异表达的初步研究." 遗传(7): 838-844.

30. 徐汉福, 王 峰, 王根洪, 段晓利, 马三垣, 夏庆友 (2011). "家蚕Poly(A)结合蛋白基因BmPABP的克隆及序列与功能分析." 蚕业科学 37(3): 412-418.

31. 杨远萍, 刘春, 王子龙, 王根洪, 夏庆友 (2006). "家蚕组织蛋白酶D基因的克隆、序列分析及其表达谱研究." 昆虫学报(2): 172-178.

联系地址：重庆市北碚区西南大学（南区）家蚕基因组生物学国家重点实验室，400716

电  话： 023-68251573

E-mail：wanggh168@swu.edu.cn