| 发布时间：2016-11-25 查看 0次 字体：[大] [中] [小] |
李春峰
博士，研究员，硕士生导师
教育经历：
1991.09-1995.06 西南农业大学 蚕学专业 本科生
1995.09-1998.06 西南农业大学 蚕学专业 硕士研究生
2001.09-2008.06 西南大学 特种经济动物饲养专业 博士研究生
工作经历：
1995－2000，西南农业大学 助教
2000－2006，西南农业大学 讲师
2006－2022，西南大学 副教授
2013－2014，密苏里大学堪萨斯分校 访问学者
2022－至今，西南大学 研究员
主要科研领域与方向：
1. 病原微生物感染与防控
2. 真菌-昆虫相互作用的分子机制
科学成就：
主要从事家蚕病原微生物感染与防控、昆虫免疫应答方面的研究。主持国家自然科学基金、重庆市自然科学基金、企业合作项目、中央高校科研业务费专项等8项课题，参与国家 “973”、“863”及重庆市重大科技专项等多个项目。先后在Microbiology Spectrum、Insect Science、Parasit Vectors、Journal Of Invertebrate Pathology、Frontiers in Microbiology、Bulletin of Entomological Research、Journal of Economic Entomology等国内外学术期刊发表研究论文70余篇。参编出版《资源昆虫及其利用》、《家蚕微孢子虫基因组生物学》、《家蚕饲养与良种繁育学》等教材及专著6部，参与《微孢子虫-机会性病原体》著作的翻译，获授权专利4项。参加完成的“家蚕微孢子虫侵染与宿主应答的分子基础”研究获得教育部高等学校科学研究优秀成果奖自然科学二等奖。
代表性论文（*通讯作者）：
1. Tong C, Li T, Luo S, Chen R, Chen S, Wei J, Qing Y, Qin S, Pan G, Li C*, Zhou Z. Detection of the pathogenic fungus Cordyceps farinosa in the Thitarodes armoricanus soil-rearing environment based on nucleic acid targets. Can J Microbiol. 2023 Jan 13. Epub ahead of print.
2. Fan Y, Bao J, Fu X, Wu P, Chen J, Huang Y, Wei J, Pan G, Li C*, Zhou Z*. The NPC Families Mediate BmNPV Entry. Microbiol Spectr. 2022 Aug 31;10(4):e0091722.
3. Zhang R, Zheng S, Huang H, Sun X, Huang Y, Wei J, Pan G, Li C*, Zhou Z. Expression of anti-NbHK single-chain antibody in fusion with NSlmb enhances the resistance to Nosema bombycis in Sf9-III cells. Bull Entomol Res. 2022 Aug;112(4):502-508.
4. Tong C, Wei J, Pan G, Li C*, Zhou Z. Study of Pathogenesis Using Fluorescent Strain of Cordyceps farinosa Revealed Infection of Thitarodes armoricanus Larvae via Digestive Tract. Insects. 2022 Nov 10;13(11):1039.
5. Ran M, Shi Y, Li B, Xiang H, Tao M, Meng X, Li T, Li C, Bao J, Pan G, Zhou Z. Genome-Wide Characterization and Comparative Genomic Analysis of the Serpin Gene Family in Microsporidian Nosema bombycis. Int J Mol Sci. 2022 Dec 29;24(1):550.
6. Fan Y, Wei J, Wang W, Li C, Pan G, Keiffer T, Bao J, Zhou Z. Utilization of Recombinant Baculovirus Expression System to Produce the RBD Domain of SARS-CoV-2 Spike Protein. Pathogens. 2022 Jun 10;11(6):672.
7. Yu B, Yang Q, Wei J, Pan G, Li C*, Zhou Z*. UDP-Glucosyltransferases Induced by Nosema bombycis Provide Resistance to Microsporidia in Silkworm (Bombyx mori). Insects. 2021 Sep 7;12(9):799.
8. Zheng S, Huang Y, Huang H, Yu B, Zhou N, Wei J, Pan G, Li C*, Zhou Z. The role of NbTMP1, a surface protein of sporoplasm, in Nosema bombycis infection. Parasit Vectors. 2021 Jan 25;14(1):81.
9. Yu B, Sang Q, Pan G, Li C*, Zhou Z. A Toll-Spätzle Pathway in the Immune Response of Bombyx mori. Insects. 2020 Sep 1;11(9):586.
10.Zheng S, Huang Y, Chen J, Wei J, Pan G, Li C*, Zhou Z. A specific molecular label for identifying mature Nosema bombycis spores. J Invertebr Pathol. 2020 Feb;170:107322.
11.Li Z, Fan Y, Wei J, Mei X, He Q, Zhang Y, Li T, Long M, Chen J, Bao J, Pan G, Li C*, Zhou Z*. Baculovirus Utilizes Cholesterol Transporter NIEMANN-Pick C1 for Host Cell Entry. Front Microbiol. 2019 Dec 5;10:2825.
12.Chowdhury M, Li CF, He Z, Lu Y, Liu XS, Wang YF, Ip YT, Strand MR, Yu XQ. Toll family members bind multiple Spätzle proteins and activate antimicrobial peptide gene expression in Drosophila. J Biol Chem. 2019 Jun 28;294(26):10172-10181.
13.Huang Y, Zheng S, Mei X, Yu B, Sun B, Li B, Wei J, Chen J, Li T, Pan G, Zhou Z, Li C*. A secretory hexokinase plays an active role in the proliferation of Nosema bombycis. PeerJ. 2018 Sep 21;6:e5658.
14.Huang Y, Chen J, Sun B, Zheng R, Li B, Li Z, Tan Y, Wei J, Pan G, Li C*, Zhou Z*. Engineered resistance to Nosema bombycis by in vitro expression of a single-chain antibody in Sf9-III cells. PLoS One. 2018 Feb 15;13(2):e0193065.
15.Pan G, Bao J, Ma Z, Song Y, Han B, Ran M, Li C, Zhou Z. Invertebrate host responses to microsporidia infections. Dev Comp Immunol. 2018 Jun;83:104-113.
16.Li Z, Pan G, Ma Z, Han B, Sun B, Ni Q, Chen J, Li T, Liu T, Long M, Li C*, Zhou Z. Comparative proteomic analysis of differentially expressed proteins in the Bombyx mori fat body during the microsporidia Nosema bombycis infection. J Invertebr Pathol. 2017 Oct;149:36-43.
17.Zhong X, Chowdhury M, Li CF, Yu XQ. Transcription Factor Forkhead Regulates Expression of Antimicrobial Peptides in the Tobacco Hornworm, Manduca sexta. Sci Rep. 2017 Jun 2;7(1):2688.
18.Li T, Pan GQ, Vossbrinck CR, Xu JS, Li CF, Chen J, Long MX, Yang M, Xu XF, Xu C, Debrunner-Vossbrinck BA, Zhou ZY. SilkPathDB: a comprehensive resource for the study of silkworm pathogens. Database (Oxford). 2017 Jan 1;2017(1):bax001.
19.Yang D, Pan L, Peng P, Dang X, Li C, Li T, Long M, Chen J, Wu Y, Du H, Luo B, Song Y, Tian R, Luo J, Zhou Z, Pan G. Interaction between SWP9 and Polar Tube Proteins of the Microsporidian Nosema bombycis and Function of SWP9 as a Scaffolding Protein Contribute to Polar Tube Tethering to the Spore Wall. Infect Immun. 2017 Feb 23;85(3):e00872-16.
20.Huang K, Li CF*, Wu J, Wei JH, Zou Y, Han MJ, Zhou ZY. Enhancer activity of Helitron in sericin-1 gene promoter from Bombyx mori. Insect Sci. 2016 Jun;23(3):396-405.
联系地址：重庆市北碚区天生路2号，西南大学家蚕基因组生物学国家重点实验室，400716
E-mail： licf@swu.edu.cn